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GHK-Cu
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GHK-Cu (Copper Peptide) is a naturally occurring tripeptide studied for wound healing, skin regeneration, and anti-aging properties.

⚠️ For research purposes only. Not for human consumption. By purchasing you confirm you are a qualified researcher.

GHK-Cu Overview

GHK-Cu (glycyl-L-histidyl-L-lysine:copper(II)) is a naturally occurring copper-binding tripeptide studied for its role in molecular signaling, matrix remodeling, and pathway dynamics. In laboratory and preclinical models, GHK-Cu has been associated with modulation of gene expression, angiogenesis, and extracellular matrix activity, making it a valuable tool for research into experimental biology.

GHK-Cu Structure

GHK-Cu molecular structure

CAS #: 89030-95-5

Molecular Formula: C₁₄Hβ‚‚β‚„CuN₆Oβ‚„

Molecular Weight: 340.9 g/mol

PubChem ID: 5311476

Research Findings

GHK-Cu has been studied in structural, epithelial, and systemic models, with research highlighting its effects on collagen synthesis, extracellular matrix dynamics, and molecular remodeling. Studies also note its role in epithelial modeling, follicle signaling, and cytokine modulation in preclinical settings.

Key Areas of Research:

  • Structural: Collagen, matrix, connective signalingEpithelial: Matrix dynamics, remodeling, follicle signalingSystemic: Cytokine modulation, viability, pathway dynamicsTogether, these findings suggest broad experimental potential for GHK-Cu across structural, epithelial, and systemic pathways. By supporting collagen formation and molecular remodeling while modulating cytokine signaling, GHK-Cu provides a versatile platform for research into matrix dynamics, epithelial biology, and systemic resilience in laboratory settings.Pickart L. et al., 2015

References

Mao S, Huang J, Li J, et al. Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms. Front Pharmacol. 2025;16:1551843. Published 2025 Jul 2. doi:10.3389/fphar.2025.1551843Wang X, Liu B, Xu Q, et al. GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis. Wound Repair Regen. 2017;25(2):270-278. doi:10.1111/wrr.12520Dou Y, Lee A, Zhu L, Morton J, Ladiges W. The potential of GHK as an anti-aging peptide. Aging Pathobiol Ther. 2020;2(1):58-61. doi:10.31491/apt.2020.03.014

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