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GLP-3R
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GLP-3R is a research peptide studied for metabolic and gastrointestinal pathway modulation in preclinical research settings.

⚠️ For research purposes only. Not for human consumption. By purchasing you confirm you are a qualified researcher.

GLP-3R Overview

GLP-3R is a synthetic investigational peptide developed as a multi-pathway agonist. It is currently being studied for its potential effects on receptor-mediated signaling, molecular dynamics, and endocrine function in preclinical research models. By activating multiple target receptor subtypes, GLP-3R demonstrates broad systemic effects under investigation for their relevance in endocrine and pathway-level research.Jastreboff A.M. et al. (2023).

GLP-3R Structure

GLP-3R molecular structure

CAS #: 2381089-83-2

Molecular Formula: C₂₂₁H₃₄₂N₄₆Oβ‚†β‚ˆ

Molecular Weight: 4845.44 g/mol

PubChem ID: 474492335

Research Findings

GLP-3R has been examined in endocrine and systemic models, with studies highlighting its influence on receptor binding kinetics, downstream signaling cascades, lipid pathway dynamics, and integrated endocrine pathways. Research also points to its role in multi-system signaling and pathway characterization in preclinical and laboratory settings.

Key Areas of Research:

  • Endocrine: Receptor binding, signaling, cascadesPathway: Target subtypes, modulation, dynamicsVascular: Lipid pathways, hepatic signaling, markersSystemic: Multi-pathway signaling, resilience, characterizationTogether, these findings suggest broad experimental potential for GLP-3R across endocrine, vascular, and systemic models. By engaging multiple pathway targets, it provides a versatile research platform for studying downstream signaling cascades and integrated molecular responses across diverse biological systems.Jastreboff A.M. et al., New England Journal of Medicine, 2023

References

Jastreboff A.M. et al. (2023). Triple-hormone receptor agonist retatrutide in obesity β€” a randomized, controlled trial. N Engl J Med, 389(1):11–24.Coskun T. et al. (2022). Retatrutide: A triple-hormone receptor agonist for obesity and diabetes. Diabetes, 71(7):1435–1449.

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