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AOD-9604
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AOD-9604 is a synthetic peptide fragment derived from the C-terminal end of human growth hormone. Studied for its role in lipolytic signaling and metabolic pathway research.

⚠️ For research purposes only. Not for human consumption. By purchasing you confirm you are a qualified researcher.

AOD-9604 Overview

AOD-9604 is a synthetic peptide fragment derived from the C-terminus of the somatotropin sequence (fragment 176–191, with an added N-terminal Tyr). It is studied for its effects on lipolytic and anti-lipogenic pathways, Ξ²3-adrenergic signaling, and downstream pathway dynamics in laboratory and preclinical models.

AOD-9604 Structure

AOD-9604 molecular structure

CAS #: 386264-39-7

Molecular Formula: Cβ‚‡β‚ˆH₁₂₃N₂₃O₂₃Sβ‚‚

Molecular Weight: 1815.1 g/mol

PubChem ID: 71300630

Research Findings

AOD-9604 has been studied in signaling, structural, and systemic models, with research exploring its effects on lipid pathway dynamics, substrate utilization, and remodeling processes. Studies also highlight its potential influence on cartilage modeling, skeletal signaling, and pathway activity in preclinical settings. Together, these findings suggest experimental potential across signaling, structural, and systemic pathways.

Key Areas of Research:

  • Signaling: Lipid pathways, substrate dynamics, Ξ²3-adrenergic
  • Structural: Cartilage, skeletal matrix, connective tissue
  • Systemic: Remodeling, viability, metabolic pathway dynamics

References

Heffernan M. et al. (2001) Effects of hGH and its lipolytic fragment (AOD-9604) on lipid metabolism in obese and Ξ²3-AR knockout mice.Ng F.M. et al. (2000) Metabolic studies of a synthetic lipolytic domain (AOD-9604) of human growth hormone.Stier H., Vos E., Kenley D. (2013) Safety and tolerability of the hexadecapeptide AOD-9604 in humans: summary of randomized, double-blind, placebo-controlled trials.

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