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Semax
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Semax is a synthetic peptide analogue of ACTH studied for neuroprotection, cognitive enhancement, and stress response modulation.

⚠️ For research purposes only. Not for human consumption. By purchasing you confirm you are a qualified researcher.

Semax Overview

Semax is a synthetic heptapeptide derived from adrenocorticotropic hormone (ACTH 4-10) with the addition of a C-terminal Pro-Gly-Pro sequence. It is studied in laboratory and preclinical models for its influence on neuronal signaling, CNS pathway dynamics, and molecular stress responses. Research has investigated its ability to modulate neurotrophic factor expression, neurotransmitter systems, and oxidative stress pathways.Ashmarin I.P. et al. (1997).

Semax Structure

CAS #: 80714-61-0

Molecular Formula: C₃₇H₅₁N₉O₁₀

Molecular Weight: 751.9 g/mol

PubChem ID: 3085694

Research Findings

Semax has been studied in neurological, CNS, and systemic models, with research highlighting its role in neuronal signaling, synaptic pathway dynamics, and stress response. Studies also report activity in neurotransmitter modulation, oxidative stress pathways, and signaling dynamics in preclinical settings.

Key Areas of Research:

  • Neurological: Neuronal signaling, pathways, cascadesCNS: Synaptic plasticity, signaling, functionSystemic: Stress pathways, remodeling, resilienceTogether, these findings suggest broad experimental potential for Semax across neurological, CNS, and systemic pathways. By influencing neurotransmitter systems and supporting signaling and pathway responses, Semax provides a versatile platform for research into CNS dynamics, stress biology, and systemic resilience in laboratory settings.Ashmarin I.P. et al., 1995

References

Ashmarin I.P. et al. (1997). Neuroactive properties of Semax in laboratory and preclinical models. Neurosci Behav Physiol, 27(5): 570–575.Inozemtsev A.N. et al. (2008). Semax and regulation of gene expression linked to synaptic plasticity and neuronal survival. Bull Exp Biol Med, 146(4): 439–442.Volodina O.L. et al. (2011). Protective effects of Semax in ischemia-reperfusion injury models. Bull Exp Biol Med, 151(2): 179–183.

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